Popular diet is seen as better than low fat option for those at risk of vascular dementia.
The authors from the University of Navarra in Spain base their findings on 522 men and women aged between 55 and 80 without cardiovascular disease but at high vascular risk because of underlying disease/conditions.These included either type 2 diabetes or three of the following: high blood pressure; an unfavorable blood fat profile; overweight; a family history of early cardiovascular disease; and being a smoker.
The Mediterranean diet is characterized by the use of virgin olive oil as the main culinary fat; high consumption of fruits, nuts, vegetables, and moderate to high consumption of fish and seafood. Those who follow it also eat a low consumption of dairy products and red meat; but have a moderate intake of red wine.
Participants had regular check-ups with their family doctor and quarterly checks on their compliance with their prescribed diet. They followed the diet for an average of 6.5 years, and were then tested for signs of cognitive decline using tests to assess higher brain functions, including orientation, memory, language, visuospatial and visuoconstrution abilities and executive functions such as working memory, attention span, and abstract thinking. The average scores on both tests were significantly higher for those following either of the Mediterranean diets compared with those on the low fat option
At the end of the study period, 60 participants had developed mild cognitive impairment: 18 on the olive oil supplemented Mediterranean diet; 19 on the diet with added mixed nuts; and 23 on the control group.A further 35 people developed dementia: 12 on the added olive oil diet; six on the added nut diet; and 17 on the low fat diet.
These findings held true irrespective of other influential factors, including age, family history of cognitive impairment or dementia, the presence of ApoE protein—associated with Alzheimer’s disease—educational attainment, exercise levels, vascular risk factors; energy intake and depression.
The authors acknowledge that their sample size was relatively small, and that because the study involved a group at high vascular risk, it doesn’t necessarily follow that their findings are applicable to the general population. But, they say, theirs is the first long term trial to look at the impact of the Mediterranean diet on brain power, and that it adds to the increasing body of evidence suggesting that a high quality dietary pattern seems to protect cognitive function in the aging brain.