Roswell: New Strategy for Treating Pancreatic Cancer

Roswell Park Team Proposes Strategy for Making Pancreatic Tumors Respond to Checkpoint Inhibition New study provides rationale for combining targeted therapies with anti-PD-L1 immunotherapy Most pancreatic cancers do not respond to immune checkpoint inhibitors In lab, combination of CDK4/6 inhibitors and MEK inhibitors slowed tumor growth Targeted

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Roswell Leads COVID-19 Treatment Approach in WNY

Collaborative Effort Brings New COVID-19 Treatment Approach to Western New York Clinical trial led by Roswell Park, UB will test effectiveness of anti-inflammatory drug Clinical trial will assess effectiveness of the antibody sarilumab (Kevzara) Part of large international COVID-19 trial sponsored by Regeneron Researchers pursuing additional clinical trials

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Roswell Park Team Discovers New Mechanism Driving Pancreatic Cancer

Length of some regions of messenger RNA plays key role in regulating gene expression, cancer growth Role revealed for little-known process known as alternative polyadenylation First large-scale single-cancer analysis of alternative polyadenylation events Changes to length of certain RNA segments can be key prognostic indicator  BUFFALO, N.Y.—

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Clinical Trials and Childhood Hodgkin Lymphoma

Access to Clinical Trials May Drive Differences in Outcome Among Childhood Hodgkin Lymphoma Patients COG study looks to explain lower survival rate for nonwhite children and adolescents with disease Study is latest to report lower survival for blacks, Hispanics with the disease Multicenter team set out to

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Reduced Therapy for Children with Neuroblastoma

Algorithm Reduces Need for Therapy in Children With Intermediate-Risk Neuroblastoma COG study shows treatment can be reduced without compromising outcomes – shows therapy can be reduced in some neuroblastoma patients Algorithm based on tumor biology, anticipated response to treatment for patients with localized tumors, 3-year overall survival

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Roswell Park Ranked 14th on List of Nation’s Best Hospitals for Cancer

Roswell Park Comprehensive Care Center

Data-driven assessment by U.S. News & World Report places Roswell Park in top 1.5% of cancer hospitals Annual ranking reviewed patient outcomes and other data for 885 cancer centers New methodology puts focus on patient-centered metrics Also rated high-performing in 2 subspecialties: colon and lung cancer surgery

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National Cancer Institute Renews Roswell Park’s Prestigious ‘Comprehensive’ Designation

Nation’s longest-standing dedicated cancer center awarded 5-year, $22.5 million grant to pursue its mission Roswell Park was among first group of 3 centers designated by NCI in 1970s Rigorous review process assesses strength of research, impact on community Largest such grant and best application score in Roswell

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Roswell Park Awarded $6 Million

Roswell Park Awarded More Than $6 Million in Moonshot Funds to Lead New Data Management Resource Team wins competitive bid to establish critical data center supporting other Moonshot projects $6.28M award funds creation of Data Management and Resource-Sharing Center Program will serve as hub for 13 other

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